Long-term efficacy and safety of asciminib in chronic-phase chronic myeloid leukemia without the T315I mutation
Asciminib provides durable molecular responses and a favorable safety profile after up to 8.4 years of treatment in heavily pretreated patients.
Hemomeeting
6 min read
October 10, 2025
Sources
- Cortes JE, Chuah C, Saussele S, Richter J, Maiti A, DeAngelo DJ, et al. Long-term safety and efficacy of asciminib in patients with chronic-phase chronic myeloid leukemia without the T315I mutation after ≥2 prior TKIs: Updated phase 1 results. Leukemia. 2025;39(1):134–147. doi:10.1038/s41375-025-02110-2
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Written by Hemomeeting
About
Hemomeeting, coordinated by Dr. Breno Gusmão, an onco-hematologist, is an initiative dedicated to the exchange of information among onco-hematology specialists from Brazil and worldwide. In a constantly evolving scientific landscape, numerous new drug options emerge annually for blood neoplasms such as lymphomas, leukemias, and multiple myeloma. The exchange of knowledge among specialists is considered essential to ensure that these advances are widely disseminated, allowing all patients access to the best available treatments.