
Cardiovascular disease (CVD) is the leading global cause of death, responsible for 17.9 million deaths each year. According to the 2025 American Heart Association (AHA) Heart Disease and Stroke Statistics Update, CVD continues to dominate as the primary cause of mortality in the U.S., despite advances in prevention and treatment.
On World Heart Day 2025, healthcare professionals are urged to strengthen evidence-based strategies to reduce cardiovascular risk, improve hypertension control, and address inequities in care delivery.
Key Modifiable Risk Factors for Cardiovascular Health
The AHA emphasizes the importance of assessing and managing eight essential cardiovascular health metrics:
- Blood pressure (BP)
- Lipids
- Glucose levels
- Body mass index (BMI)
- Sleep quality
- Nicotine exposure
- Diet
- Physical activity
Effective management of these factors significantly reduces CVD incidence and adverse outcomes.
Hypertension Control: Team-Based Care and Fixed-Dose Combinations
Team-Based Care
Hypertension is one of the most prevalent and modifiable contributors to CVD, affecting nearly half of U.S. adults. Evidence supports team-based care models, where multidisciplinary teams collaborate with patients and primary providers. These models have been shown to:
- Improve blood pressure control
- Increase treatment adherence
- Deliver greater benefits in underserved and minority populations
Fixed-Dose Combination Therapy
Fixed-dose combinations (FDCs)—single pills combining two or more antihypertensive agents—are effective in:
- Enhancing patient adherence
- Reducing blood pressure more effectively than monotherapy
- Simplifying regimens and reducing side effects
These therapies are especially valuable for patients at high cardiovascular risk.
Addressing Health Equity in Cardiovascular Care
Disparities in CVD outcomes are closely linked to social determinants of health, including:
- Structural racism
- Economic inequities
- Limited access to healthcare
To close these gaps, health systems should prioritize:
- Culturally competent care
- Resource allocation to high-burden communities
- Policy advocacy aimed at dismantling barriers to equitable care
Conclusion
World Heart Day 2025 reinforces the need for clinicians to adopt evidence-based strategies for CVD prevention and management. Embracing team-based care models, leveraging fixed-dose combination therapy, and prioritizing equity-driven interventions are essential to improving cardiovascular outcomes worldwide.
Stay updated with the latest evidence and explore more articles on cardiovascular health and medical education.
References
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2. Centers for Disease Control and Prevention (CDC). About Rabies—U.S. Human Risk; Bats as Leading Source.
3. CDC. Protecting Public Health—Rabies Animal Cases in U.S. (~4,000/year).
4. Global Alliance for Rabies Control (GARC). World Rabies Day 2025: You, Me, Community.
5. Food and Agriculture Organization of the United Nations (FAO), World Organisation for Animal Health (WOAH), WHO Joint Rabies Initiatives.
6. CDC. Global Rabies: What You Should Know.




